Effects of the Application of a Hyper-oxygenated Gel After Oral Surgery

Launched by AZIENDA OSPEDALIERA DI PERUGIA · Jun 12, 2024

Keywords

ClinConnect Summary

This clinical trial is investigating whether applying a special gel called Novox® Drop on surgical wounds can help patients feel better after having their lower wisdom teeth (third molars) removed. The researchers want to see if this gel can reduce problems like pain, swelling in the face, and difficulty in opening the mouth (known as trismus) compared to a regular gel that doesn’t have the active ingredients.

To participate in this study, you need to be between 18 and 35 years old, in good health, and able to understand Italian. You should also be scheduled to have both lower wisdom teeth removed. However, some individuals may not be eligible, such as those with certain health conditions like diabetes or high blood pressure, or if you are pregnant. If you join the trial, you will receive either the Novox® Drop gel or a placebo gel after your surgery, and researchers will monitor your recovery to see how well the gel works. This study is currently recruiting participants, so if you meet the criteria, you might have the chance to help improve post-surgery care for others!

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • good systemic and local health conditions of the patient;
• • age between 18 and 35 years;
• • understanding of the Italian language,
• • indications for the extraction of impacted bilateral lower third molars (38 and 48) according to the criteria reported in the classifications of Winter and that of Pell and Gregory;
• • the root of the impacted third molars is completely formed.
• Exclusion Criteria:
• • diabetes mellitus;
• • systemic arterial hypertension;
• • hyperthyroidism;
• • osteoporosis;
• • immunosuppressed;
• • osteonecrosis of the jaws;
• • pregnancy;
• • patients with mandibular third molars in position C according to "the Pell \& Gregory Classification" on the radiological measurements (angles and positions) for which third molar extraction surgery is required.;
• • local alterations such as pericoronitis, odontogenic cysts and tumors in relation to the third molars;
• • allergies;
• • ordinary use of analgesics or antibiotics by the patient.