Application of THRIVE in Burn Children With Suspected Difficult Airway

Launched by SHUXIU WANG · Jun 10, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at a new technique called THRIVE, which stands for transnasal humidified rapid-insufflation ventilatory exchange, to see if it can help children with burns in their head, face, or neck. The goal is to make it easier to insert a breathing tube (intubation) for these children, especially since they might have a difficult airway due to their injuries. Researchers want to find out if using THRIVE can help doctors successfully intubate these children on the first try without causing a drop in oxygen levels.

To participate in this study, children must be under 18 years old and have certain types of burns or injuries on their head, face, or neck. They should not have other serious health issues or injuries that would make the procedure too risky. If eligible, participants will receive anesthesia, then have a special nasal device placed in their nose to help keep their oxygen levels stable during the intubation process. The study aims to compare the success rates of the THRIVE technique with standard care to determine if it truly makes a difference in these challenging situations.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • \< 18 years
• • ASA Grade I \~ III
• • Children with head, face and neck scald or burn or flame or electrical c hemical or other
• Exclusion Criteria:
• • Refusal or failure to sign an informed consent
• • Proposed to transnasal intubation
• • Fracture of the nasal bone, nasal bleeding, nasal deformity or obstruction
• • Tracheotomy status or severe head, face and neck burn or burn scar (difficult airway)
• • Unsuitable for rapid sequence induction
• • Basicranial fracture
• • Cyanotic congenital heart defect
• • At risk of malignant hyperthermia
• • And is participating in other clinical studies