Adherence to Medication in Patients With Acute Decompensated Heart Failure

Launched by UNIVERSITÄT DES SAARLANDES · Jun 10, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how well patients with acute heart failure are sticking to their prescribed heart failure medications. Heart failure can worsen for many reasons, and one of them may be that patients are not taking their medications as directed. Researchers want to see how often patients are adhering to their medications using a precise testing method at the emergency department. They will also use questionnaires to understand what might affect a patient's ability to take their medications regularly.

To be eligible for this study, participants must be at least 18 years old and have a known history of chronic heart failure. They should require intravenous diuretics, which are medications that help remove excess fluid, and they must have been stable on their heart failure medications for at least two weeks. Additionally, participants need to show at least one sign of fluid overload, like swelling or difficulty breathing, and have elevated levels of a specific protein in their blood. If you join this trial, you can expect to provide some information about your health and medications, while also contributing to important research that could help improve care for others with heart failure.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • age ≥18 years of age
• • known chronic heart failure irrespective of ejection fraction (heart failure with reduced, mildly reduced, or preserved ejection fraction)
• • requirement of intravenous diuretics (outpatient or stationary treatment)
• • stable heart failure medication \>2 weeks
• • ≥1 sign of volume overload (peripheral edema, jugular venous distension, pulmonary rales, ascites, or demonstration of pulmonary venous congestion on chest X-ray)
• • elevated natriuretic peptides (N-terminal pro brain natriuretic peptide= nt-pro-BNP ≥125 pg/ml)
• Exclusion Criteria:
• • - Not able to give written informed consent