Position Intervention to Reduce Hypoxemia in Sedation Patients

Launched by FIRST AFFILIATED HOSPITAL OF ZHEJIANG UNIVERSITY · Jun 10, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how changing a patient's body position can help prevent low oxygen levels (called hypoxemia) during sedation. Hypoxemia can lead to serious problems like heart rhythm issues, nausea, and confusion. The researchers believe that by simply adjusting how patients are positioned, especially in emergency situations or places with limited medical resources, they can improve breathing and overall safety without needing complicated treatments.

To participate in this trial, you need to be at least 18 years old and not have any major heart or lung problems. You should also be scheduled for a procedure or surgery that requires sedation. If you have certain medical conditions, like severe heart disease or bleeding disorders, or if you cannot change your body position, you may not be eligible. Participants in the trial will be informed about what to expect, and they will need to sign a consent form to take part. This study aims to find a simple and effective way to keep patients safe during procedures that involve sedation.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patients with 18 years or older
• • 2. Without obvious cardiovascular or pulmonary dysfunction
• • 3. Scheduled to undergo procedure or surgery with sedation
• • 4. Signed the informed consent form
• Exclusion Criteria:
• • 1. Preexisting bradycardia (heart rate \<50 beats/min), hypotension (systolic blood pressure \< 80mmHg), or hypoxemia (SpO2 \< 90%);
• • 2. Requiring supplemental chronic or intermittent oxygen therapy because of preexisting diseases
• • 3. Preexisting diseases which unable to tolerate reduced SpO2 or Partial pressure of carbon dioxide in artery (PaCO2) diseases, such as severe cardiovascular and cerebrovascular diseases, intracranial hypertension or severe lung diseases;
• • 4. Coagulation disorders or a tendency of nose bleeding;
• • 5. Patients whose body position cannot be altered;
• • 6. Participated in other intervention clinical studies in the past 3 months;
• • 7. Other conditions deemed unsuitable for inclusion by the researcher;
• • 8. Patients and guardians refused to participate in this trial.