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Search / Trial NCT06459297

Study of Oral Upadacitinib to Assess Change in Disease Activity and Adverse Events in Adult Participants With Ulcerative Colitis or Crohn's Disease

Launched by ABBVIE · Jun 11, 2024

Trial Information

Current as of August 31, 2025

Recruiting

Keywords

Inflammatory Bowel Diseases Upadacitinib Rinvoq Ulcerative Colitis Crohn's Disease

ClinConnect Summary

This clinical trial is studying a medication called upadacitinib to see how well it works for adults with moderate to severe ulcerative colitis or Crohn's disease. Both of these conditions cause long-term inflammation in the digestive system, and the trial aims to find out if upadacitinib can help reduce disease activity and if there are any side effects from the treatment. The study will include about 600 adult participants in Korea who are already prescribed upadacitinib by their doctor.

To be eligible for the trial, participants must have a diagnosis of either ulcerative colitis or Crohn's disease and be suitable for upadacitinib treatment. They should not have any conditions that would prevent them from taking this medication or be involved in other clinical studies. Participants can expect to attend regular check-ups at a hospital or clinic over the course of up to 52 weeks, but there should be no extra burden from participating in this trial.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Participants diagnosis with ulcerative colitis or Crohn's Disease suitable for the treatment with Upadacitinib.
  • Participants prescribed upadacitinib in accordance with the approved local label.
  • Exclusion Criteria:
  • Participants with any contraindication to Upadacitinib.
  • Participants currently participating in another clinical research not including observational study.

About Abbvie

AbbVie is a global biopharmaceutical company dedicated to developing innovative therapies that address complex health challenges. Founded in 2013 as a spin-off from Abbott Laboratories, AbbVie focuses on key therapeutic areas, including immunology, oncology, neuroscience, and virology. The company is committed to advancing scientific research and delivering groundbreaking treatments that enhance patient outcomes and quality of life. With a robust pipeline and a strong emphasis on collaboration, AbbVie strives to transform the future of medicine through its commitment to clinical excellence and patient-centered approaches.

Locations

Daejeon, Daejeon Gwang Yeogsi, Korea, Republic Of

Seoul, Seoul Teugbyeolsi, Korea, Republic Of

Cheonan Si, Chungcheongnamdo, Korea, Republic Of

고양시, Gyeonggido, Korea, Republic Of

Daegu, Gyeongsangbugdo, Korea, Republic Of

Gwangju, Jeonranamdo, Korea, Republic Of

Dongdaemun Gu, Seoul Teugbyeolsi, Korea, Republic Of

Seoul, Seoul Teugbyeolsi, Korea, Republic Of

Seoul, Seoul Teugbyeolsi, Korea, Republic Of

Seoul, Seoul Teugbyeolsi, Korea, Republic Of

Ulsan, Ulsan Gwang Yeogsi, Korea, Republic Of

Daegu, , Korea, Republic Of

중구, , Korea, Republic Of

Seoul, Seoul Teugbyeolsi, Korea, Republic Of

Patients applied

0 patients applied

Trial Officials

ABBVIE INC.

Study Director

AbbVie

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported