Cold Snare Piecemeal Resection vs Cold Snare Endoscopic Mucosal Resection

Launched by INDIANA UNIVERSITY · Jun 12, 2024

Keywords

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Gender

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Eligibility criteria

• Inclusion Criteria:
• • 1. ≥ 18 years of age
• • 2. Presenting for a screening, surveillance, diagnostic, or therapeutic colonoscopy
• 3. Found to have:
• • a sessile serrated lesion or hyperplastic polyp ≥ 10 mm during procedure (Serrated Cohort) or
• • a 10-19 mm conventional adenoma during procedure (Adenoma Cohort)
• • 4. Ability to provide informed consent
• Exclusion Criteria:
• • 1. Pedunculated or semi-pedunculated polyps (as defined by Paris Classification type Ip or Isp)
• 2. Polyps confirmed to be anything other than:
• • sessile serrated lesion or hyperplastic polyp on histologic diagnosis (Serrated Cohort) or
• • conventional adenoma on histologic diagnosis (Adenoma Cohort)
• • 3. Patients with Ulcerative Colitis or Crohn's disease
• • 4. Polyps with features suggestive of submucosal invasion
• • 5. Polyps that are not able to be removed endoscopically due to location (e.g. extending into appendiceal orifice or diverticulum)
• 6. Patients with a known or suspected diagnosis of any of the following polyposis syndromes with known genetic mutations:
• • Familial Adenomatous Polyposis Syndrome
• • MUTYH associated Polyposis Syndrome
• • Juvenile Polyposis Syndrome
• • Cowden's Syndrome
• • Peutz-Jeghers Syndrome
• • 7. Subjects whose colonoscopy procedure is not able to be completed due to bowel prep precluding polyp identification.