A Clinical Trial to Compare Lasotronix Alone or in Combination With CPP-ACP to Treat DH
Launched by DOW UNIVERSITY OF HEALTH SCIENCES · Jun 14, 2024
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying a treatment for dentin hypersensitivity (DH), which is a sharp pain that can occur in your teeth when they are exposed to hot, cold, or certain foods. The researchers are looking at two different approaches: using a special laser called LASOTRONIX alone, or using it together with a product called Casein Phosphopeptide paste (CPP-ACP). This trial is important because it aims to find out how effective these treatments are for helping people who suffer from DH.
To participate in this trial, you need to be between 25 and 65 years old and have at least one sensitive tooth that is healthy (no cavities or broken fillings). However, if you’ve used any desensitizing treatments, antibiotics, or anti-inflammatory medications in the past six months, or if you're pregnant or smoke, you won't be eligible to join. If you decide to participate, you can expect to receive one of the treatments and follow up with the research team to see how well it works for you. This trial is currently looking for volunteers, and your involvement could help improve treatments for others with similar dental issues in the future.
Gender
ALL
Eligibility criteria
- Inclusion criteria:
- • Patients of either gender, with ages between 25-65 years
- • should have at least more than one hypersensitive and vital tooth without any carious lesion or defective restoration
- Exclusion criteria:
- • History of desensitizing therapy on the affected tooth/teeth in last six months (use of desensitizing toothpaste)
- • use of antibiotics /analgesic/anti-inflammatory drugs
- • history of smoking
- • pregnancy
- • those who are not willing to participate or give follow-ups
About Dow University Of Health Sciences
Dow University of Health Sciences (DUHS) is a premier educational and research institution based in Karachi, Pakistan, dedicated to advancing healthcare through innovative research and clinical excellence. As a clinical trial sponsor, DUHS integrates cutting-edge scientific inquiry with practical applications, fostering a collaborative environment that promotes the development of new treatments and therapies. The institution is committed to upholding the highest ethical standards in research, ensuring participant safety, and contributing to the global body of medical knowledge. With a focus on interdisciplinary collaboration and community health impact, DUHS plays a pivotal role in enhancing the quality of healthcare both locally and internationally.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Karachi, Sindh, Pakistan
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported