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Search / Trial NCT06463964

Predictors of Acute Kidney Injury in Patients With Acute Decompensated Heart Failure in Emergency

Launched by SOHAG UNIVERSITY · Jun 14, 2024

Trial Information

Current as of July 22, 2025

Enrolling by invitation

Keywords

ClinConnect Summary

In the past few years, investigators have reported that AHF patients might experience "congestion", named to describe signs and symptoms of extracellular fluid accumulation that results in increased cardiac filling pressure. This triggers compensatory mechanisms such as the renin-angiotensin-aldosterone system, sympathetic nervous system, and other local mediators. These compensatory mechanisms interact to maintain fluid volume and "renal congestion" has been recognized as part of systemic congestion. Renal congestion, resulting from lower cardiac output, tubule glomerular feedback, increas...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Aged \>18 Yrs Both Sexes Patients with ADHF
  • Exclusion Criteria:
  • Patients udnergoing maintenance renal replacment therapy (RRT) such as hemodialysis and peritoneal dialysis History of CKD Kdiney transplantation Undergoing opeartions within 1 week before and after AKI events Drug Toxicity Rheumatologic or auto immune disease Acute infection Diretic therapy of radio-opaque contrast media in the last 15 days History of aminoglycosides, metformin and nonsteroid anti inflammatory drugs in the last 7 days Thyroid dysfunction

About Sohag University

Sohag University is a distinguished academic institution located in Sohag, Egypt, committed to advancing healthcare through rigorous clinical research. As a clinical trial sponsor, the university leverages its robust infrastructure and multidisciplinary expertise to facilitate innovative studies aimed at improving patient outcomes and contributing to the global body of medical knowledge. With a focus on ethical standards and scientific integrity, Sohag University collaborates with healthcare professionals and researchers to conduct trials that address critical health issues, ensuring the advancement of evidence-based practices in the healthcare community.

Locations

Sohag, , Egypt

Patients applied

0 patients applied

Trial Officials

Magdy M Amin, Professor

Principal Investigator

Sohag University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported