Dexmedetomidine Versus Midazolam-Fentanyl for Analgesia and Sedation
Launched by EGYMEDICALPEDIA · Jun 12, 2024
Trial Information
Current as of August 23, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is comparing two medications, dexmedetomidine and midazolam-fentanyl, to see which one is better for helping patients feel relaxed and comfortable after heart valve surgeries. After such surgeries, many patients need help with sedation to ease their anxiety and discomfort during recovery, especially when they are on a ventilator. The goal is to find out which medication can help patients recover faster and more comfortably.
To participate in this study, patients must be adults scheduled for elective (planned) heart valve surgeries. Unfortunately, those who have emergencies, certain health conditions like uncontrolled diabetes or liver problems, or who are allergic to the study drugs cannot join. If someone is eligible, they can expect to receive either dexmedetomidine or midazolam-fentanyl during their recovery and contribute to important research that could improve care for future heart surgery patients.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • - This study will include patients undergoing elective adult valvular cardiac surgeries
- Exclusion Criteria:
- • Patient refusal.
- • Emergent valve cardiac surgeries.
- • Patients with known hypersensitivity to study drugs.
- • History of uncontrolled diabetes or hypertension.
- • Impaired kidney or liver functions.
- • Perioperative hemodynamic instability.
About Egymedicalpedia
eGymedicalpedia is a leading clinical trial sponsor dedicated to advancing medical research and innovation. With a focus on enhancing patient outcomes, eGymedicalpedia specializes in the design, implementation, and management of clinical trials across various therapeutic areas. The organization leverages cutting-edge technology and a robust network of healthcare professionals to ensure compliance with regulatory standards while prioritizing patient safety. Committed to transparency and collaboration, eGymedicalpedia aims to accelerate the development of groundbreaking treatments and therapies that address unmet medical needs.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Cairo, , Egypt
Patients applied
Trial Officials
Mohammed Ibrahim Mohammed Hashish, Professor
Study Chair
Al-Azhar University, Faculty of medicine
Mohamed husseiny Mahmoud, Lecturer
Principal Investigator
Cardio-Thoracic Surgery Department, Al-Azhar University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported