Opioid-based Versus Opioid-free Endotracheal Intubation

Launched by ARETAIEION UNIVERSITY HOSPITAL · Jun 13, 2024

Keywords

ClinConnect Summary

This clinical trial is studying the effects of two different methods of anesthesia during surgery: one that uses opioids (strong pain-relieving medications) and one that does not. The goal is to see how these methods affect patients’ blood pressure and pain levels when they are given anesthesia for elective (planned) surgeries. Researchers are looking for adult patients between the ages of 18 and 75 who are generally healthy and meet specific criteria related to their physical health.

If you or a family member are considering joining this trial, you should know that it is currently recruiting participants. Eligible individuals should not have certain health issues, such as a history of severe heart problems or difficulties with their airway. Participants can expect to undergo a standard procedure for anesthesia, and their responses will be monitored closely to help understand which method may be better for patients. This study aims to improve the safety and comfort of anesthesia for future surgeries.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • adult patients
• • American Society of Anesthesiologists (ASA) classification I-II
• • Mallampati classification 1, 2 or 3
• Exclusion Criteria:
• • anticipated difficult airway (Mallampati 4 classification, thyromental distance \< 6 cm, mouth opening \< 3 cm, neck extension\< 80
• • atrioventricular block
• • bradycardia (heart rate less than 55/min)
• • preadministration of beta-blockers
• • eligibility for rapid-sequence induction
• • chronic use of opioid medications
• • known allergy to induction agents
• • history of psychiatric disease
• • language or communication barriers or lack of informed consent