Effects of ITBS Combined with NMES on Dysphagia After Stroke

Launched by THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIVERSITY · Jun 17, 2024

Keywords

ClinConnect Summary

The purpose of this study is to observe the effect of intermittent Theta Burst Stimulation (iTBS) combined with neuromuscular electrical stimulation (NMES) on patients with dysphagia (PSD) after stroke, and to detect the activation of related swallowing networks in patients with PSD after receiving iTBS combined with NMES by functional near-infrared spectroscopy (fNIRS), and to explore the possible mechanism of PSD treatment, so as to provide a theoretical basis for finding the best, specific and individualized treatment plan for the treatment of PSD patients. Promote the functional recover...

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Eligibility criteria

• Inclusion Criteria:
• • 18 \~80 years old;
• • The patients met the diagnostic criteria of stroke in the "Diagnostic Points for Major Cerebrovascular Diseases in China 2019" formulated by the Chinese Society of Neurology, and were confirmed by head CT or MRI;
• • The patients met the diagnostic criteria of dysphagia in the "Chinese Expert Consensus on the Evaluation and treatment of Dysphagia (2017 edition)" and were confirmed by VFSS;
• • The disease duration ranged from 2 weeks to 6 months;
• • The vital signs of the patient were stable;
• • The score of mini-mental state examination (MMSE) was more than 17 points for the illiterate, more than 20 points for the primary scholar, and more than 24 points for the secondary school or above;
• • Can independently or under the auxiliary balance the seat 30 minutes or more;
• • The skull was intact without craniotomy and/or cranioplasty;
• • Informed consent was obtained from all subjects or their families.
• Exclusion Criteria:
• • A history of other diseases that may cause dysphagia, such as Parkinson's disease, head and neck radiotherapy, or other neurological diseases;
• • Contraindications to iTBS or NMES with a history of epilepsy, intracranial metal implants, bleeding tendency, etc.;
• • Skin damage and infection on the front of the neck affect the placement of the surface electrode;
• • Such as fever, important viscera function failure condition is not stable, or critically ill.