Mechanisms for Atrial Fibrillation in Obstructive Sleep Apnea

Launched by DANDERYD HOSPITAL · Jun 17, 2024

Keywords

ClinConnect Summary

This clinical trial is studying the connection between atrial fibrillation (AF), a common heart rhythm disorder, and obstructive sleep apnea (OSA), a condition where breathing repeatedly stops and starts during sleep. Researchers want to understand why people with OSA are more likely to develop AF and how factors like high blood pressure and stiffness in the arteries might play a role. The goal is to find out if screening for OSA in AF patients can help prevent new cases of AF and reduce the chances of AF coming back after treatment.

If you are over 18 and scheduled for a procedure to treat your AF, you might be eligible to participate in this study. Participants will undergo several tests, including sleep studies and heart monitoring, to gather important information about their heart and how it relates to sleep apnea. You will be followed up at 3, 6, and 12 months after your procedure to see how well your heart is doing. The hope is that by better understanding the links between these conditions, doctors can provide more effective treatments and improve the quality of life for patients with AF and OSA.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients \>18 years scheduled for AF ablation or cardioversion
• Exclusion Criteria:
• • diagnosis of AF for more than 7 years
• • previous cardiac surgery including AF ablation
• • severe valvular heart disease
• • diagnosed structural heart disease
• • systolic function in sinus rhythm \<50%.
• • severe hypertensive heart disease or known hypertrophic heart disease (amyloidosis, hereditary hypertrophic heart disease)
• • invalidating chronic diseases imaging material on echocardiography not of sufficient quality.