Investigating ACute HeArt FailuRe Decongestion Guided by Lung UltraSonography

Launched by ANTONIO LEIDI · Jun 13, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at a new way to help patients with acute heart failure, which is a serious condition where the heart can't pump enough blood. The researchers want to see if using lung ultrasonography (a type of ultrasound to examine the lungs) can help doctors better manage fluid buildup in the lungs. By using this method, they hope to find out if patients can leave the hospital sooner, have fewer return visits to the hospital, and feel better overall.

To be eligible for this trial, participants need to be at least 18 years old and have been diagnosed with heart failure that causes fluid in the lungs. They should be admitted to specific hospital units for treatment. However, certain conditions, like severe low blood pressure or specific lung diseases, may prevent someone from participating. If you join the trial, you'll receive care guided by lung ultrasounds, and researchers will track how well this approach works compared to regular physical exams. Your involvement could help improve treatment for heart failure patients in the future!

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • ≥ 18 years old
• • Planned or actual admission to intermediate care units, general internal medical or cardiology wards
• • Diagnosis of congestive AHF on admission chart (primary or secondary diagnosis)
• • Raised value of N terminal-pro-brain natriuretic peptide (≥1000 ng/l).
• Key Exclusion Criteria:
• • Known isolated right heart failure
• • Systolic blood pressure \<90 mmHg, mean arterial pressure \<65 mmHg at the moment of inclusion
• • The following conditions mimicking lung cardiogenic oedema on LUS if known at inclusion and documented: Interstitial lung disease, lung cancer or metastasis, acute respiratory distress syndrome, pulmonary contusion
• • Known virologically confirmed SARS-CoV-2 pneumonia in the preceding 3 months
• • Unwillingness to give consent
• • Subjects who are pregnant or breastfeeding
• • Hospitalisation for palliative care and probable end-life within 30 days