Precision Sensorimotor Neurorehabilitation Through Personalized Stimulation Loops

Launched by UNIVERSITY OF ZURICH · Jun 13, 2024

Keywords

ClinConnect Summary

This clinical trial, called StimuLOOP.S, is investigating new ways to help stroke patients improve their walking ability. Stroke can lead to difficulties with movement, and while there are treatments available, they often work differently for each person. This study aims to personalize rehabilitation by using two innovative techniques. The first method provides real-time feedback to help patients improve specific movements based on their individual needs. The second method involves using sounds during sleep to help strengthen the motor skills learned during therapy.

To be eligible for the study, participants must be at least 18 years old and have experienced a stroke with walking difficulties for more than 30 days but less than 6 months ago. They should be able to walk with some assistance but not require total help. Participants will receive tailored therapy aimed at enhancing their walking skills, and the study hopes to demonstrate that these personalized approaches can lead to better recovery outcomes. If you or a loved one is interested, it's essential to discuss eligibility and details with a healthcare provider.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Ischemic stroke or intracerebral hemorrhage with a gait deficit older than 30 days but not more than 6 months.
• • Functional Ambulation Category ≥3
• • ≥18 years of age
• • Informed consent as documented by signature
• Exclusion Criteria:
• • Cognitive impairment, Montreal Cognitive Assessment (MoCa) \< 20
• • Comprehensive aphasia precluding the understanding of study-related information
• • Previous stroke that caused sustained clinically relevant cognitive, visual and/or gait deficits
• • Expected acute hospitalization during the training period
• • History of a physical or neurological condition that interferes with study procedures
• • Social and/or personal circumstances that interfere with the ability to return for therapy sessions and follow-up assessments
• • Not capable of voluntary gait adaptation
• • Allergy to nickel
• • Patients taking benzodiazepines or Z-drugs with a significant effect on sleep EEG