Comparing Train-of-Four Recovery in the Adductor Pollicis Versus the Adductor Digiti Minimi in Elective Surgery Patients

Launched by UNIVERSITY OF NORTH CAROLINA, CHAPEL HILL · Jun 14, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how well two different muscles in the hand recover from anesthesia after surgery. Specifically, it compares the recovery of the adductor pollicis muscle (which helps move the thumb) and the adductor digiti minimi muscle (which helps move the little finger). Doctors want to see if there are differences in how quickly these muscles regain strength after being relaxed by medication during surgery. This information could help improve the way anesthesia is monitored and managed in the future.

To participate in this study, you need to be between the ages of 65 and 74 and scheduled for surgery that requires general anesthesia and certain medications that relax your muscles. You will not be able to join if you have a neuromuscular disease, cannot use one of your arms, or are allergic to the muscle-relaxing medications. If you are eligible and choose to participate, you can expect to have monitors placed on both arms during your recovery to measure how well your muscles are regaining function, all while receiving standard care for your surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Surgery and general anesthesia with administration of non depolarizing neuromuscular blocking drug
• Exclusion Criteria:
• • neuromuscular disease or weakness of one of upper limbs.
• • Inability to use one of subjects arms to record neuromuscular monitor.
• • Contraindication to administration or allergy to non depolarizing neuromuscular blocking drug.