Combination of Micropulse Laser With or Without Photodynamic Therapy for Chronic Central Serous Chorioretinopathy

Launched by BEIJING HOSPITAL · Jun 15, 2024

Keywords

ClinConnect Summary

This clinical trial is studying the effects of two different treatment methods for a condition called chronic central serous chorioretinopathy (CSC), which can cause vision problems. The trial will compare results from patients who receive a micropulse laser treatment on its own with those who receive the same laser treatment along with a type of therapy called photodynamic therapy that does not involve any medications. The researchers will look at how these treatments affect patients' vision and the fluid in their eyes over a period of 1 to 6 months after treatment.

To be eligible for this trial, participants must be at least 18 years old and have been diagnosed with chronic CSC for more than six months. They should not have received any other laser or surgical treatments in the six months prior to joining the study. Participants can expect to have their vision and eye health monitored before and after the treatment, allowing researchers to gather important information about how well each treatment works. Additionally, the trial aims to identify factors that might affect treatment success, which could help improve future care for patients with this condition.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age \>18 years old.
• • The patient diagnosed with chronic central serous chorioretinopathy with a history of more than 6 months. The diagnostic criteria for chronic CSC were as follows: FFA examination showed leakage of strong fluorescent spots with the extension of angiography time, and late fluorescence accumulation, accompanied by decreased central vision, darkening of vision, and deformable microopia. Fundus examination showed superficial detachment of retinal neuroepithelium in macula.
• • Patients received single micropulse laser therapy or micropulse laser combined with drug-free photodynamic therapy, and had not received other laser or surgical treatment in the six months prior to treatment.
• • Patients had follow-up data before and after treatment for 1 month and at least 6 months.
• Exclusion Criteria:
• • Patients with other fundus diseases or refractive interstitial opacity.
• • During treatment, other treatments other than micropulse laser or drug-free photodynamic therapy were received.
• • Various reasons led to incomplete patient data.