ECMO ABI Detection with Hyperfine

Launched by CHILDREN'S MERCY HOSPITAL KANSAS CITY · Jun 20, 2024

Keywords

ClinConnect Summary

This clinical trial, called "ECMO ABI Detection With Hyperfine," is studying brain injuries in children who are on a special life-support machine called ECMO (Extracorporeal Membrane Oxygenation). The main goal is to understand how common these brain injuries are and what types occur after starting ECMO treatment. Researchers will also look at how these injuries develop over time and compare findings from a new type of MRI scan that can be done at the bedside with regular imaging tests that are usually performed in the hospital.

Children aged 0 to 17 who are admitted to specific intensive care units and require ECMO support may be eligible to participate in this trial. However, some children may not qualify if they are pregnant or have certain medical devices, like pacemakers or cochlear implants, that could interfere with the MRI scan. If they join the study, participants can expect to have additional MRI scans to monitor their brain health while receiving ECMO treatment, helping doctors learn more about how to care for patients in the future.

Gender

ALL

Eligibility criteria

• • Inclusion Criteria
• • Participants that will be or are admitted to the Pediatric Intensive Care Unit, Cardiac Intensive Care Unit, or the Neonatal Intensive Care Unit
• • Ages 0-17 years
• • Participants that are at high risk for undergoing ECMO or are currently undergoing venovenous or venoarterial ECMO
• • High risk participants include, but are not limited to:
• • Undergoing cardiac surgery
• • Congenital heart disease
• • Congenital diaphragmatic hernia
• • Refractory hypoxemic and/or hypercarbic respiratory failure
• • Vasoactive-refractory shock
• • Exclusion Criteria
• • Pregnancy
• * Active implants such as:
• • Pacemaker
• • Implanted defibrillator
• • Implanted insulin pump
• • Deep brain stimulator
• • Vagus nerve stimulator
• • Cochlear implant
• • Programmable shunt
• • MRI incompatible surgical hardware (e.g., staples, screws, etc.)
• • Metal-containing tattoos or permanent make-up on head or neck
• • Suspected metal in eye, e.g.,
• • Former or current welders, metal workers, or individuals with a metal injury
• • Metal shrapnel
• • Passive implants are considered MRI-conditional