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Search / Trial NCT06471062

Transit Time Flow Measurement in Coronary Surgery

Launched by FONDAZIONE POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI IRCCS · Jun 17, 2024

Trial Information

Current as of July 22, 2025

Not yet recruiting

Keywords

Coronary Artery Bypass Transit Time Flowmetry Intraoperative Epicardial High Frequency Ultrasound (Hfus) Coronary Anastomosis Patency

ClinConnect Summary

This clinical trial is studying how the quality of two different grafts used in heart surgery might affect each other. Specifically, it looks at whether a new graft placed in an area different from the heart's left anterior descending artery (LAD) influences the performance of the graft made from the left internal mammary artery, which is connected to the LAD. The researchers are using a special technique called transit-time flowmetry (TTFM) to measure the blood flow through these grafts during coronary artery bypass surgery.

To participate in the study, individuals must be over 18 years old, provide informed consent, and be scheduled for coronary artery bypass grafting due to stable or unstable angina, or a type of heart attack called NSTEMI. However, those who cannot give consent, are having emergency surgery, or have certain medical conditions may not be eligible. Participants can expect to contribute to important research that could improve heart surgery outcomes, but the trial is not yet recruiting patients.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • age \> 18 years;
  • informed consent acquired and registered;
  • patients who undergo coronary artery bypass grafting (with or without cardiopulmonary bypass);
  • patients with stable angina, unstable angina or acute coronary syndrome without elevation of the ST tract (NSTEMI)
  • Exclusion Criteria:
  • patients unable to give informed consent;
  • patients undergoing emergency surgery;
  • patients in unstable haemodynamic conditions or in need of pharmacological or mechanical support;
  • patients undergoing combined surgery;
  • patients undergoing single aortocoronary bypass surgery

About Fondazione Policlinico Universitario Agostino Gemelli Irccs

Fondazione Policlinico Universitario Agostino Gemelli IRCCS is a leading research and healthcare institution based in Rome, Italy, renowned for its commitment to advancing medical science and improving patient care. As a prominent academic medical center affiliated with the Catholic University of the Sacred Heart, it integrates clinical practice, education, and research, fostering innovation in various fields of medicine. The foundation conducts a wide range of clinical trials aimed at developing new therapies and enhancing treatment protocols, with a focus on translational research that bridges the gap between laboratory discoveries and patient care. Its multidisciplinary approach and dedication to high ethical standards position it as a key player in the landscape of clinical research and healthcare improvement in Italy and beyond.

Locations

Roma, , Italy

Patients applied

0 patients applied

Trial Officials

federico cammertoni

Principal Investigator

Fondazione Policlinico Gemelli IRCCS

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported