Muscle-tendon Interaction in the Spastic Sural Triceps During Gait
Launched by NANTES UNIVERSITY HOSPITAL · Jun 19, 2024
Trial Information
Current as of August 21, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at how the muscles and tendons in the calf behave during walking in people who have had a stroke or a spinal cord injury. Researchers want to understand how the length of these muscles and tendons changes when a person walks, especially during the stance phase, which is when the foot is on the ground. They will compare the movement in these patients to that of healthy individuals to see how it differs.
To participate, individuals must be adults who have had a stroke at least a week ago or have an incomplete spinal cord injury, with some ability to move their legs. Those who are healthy and have no neurological issues are also welcome to join the study. Participants will undergo tests that include ultrasound imaging and 3D gait analysis, which will help the researchers gather detailed information about their walking patterns. It's important to note that certain medical histories, like recent surgeries or specific health conditions, might exclude someone from participating.
Gender
ALL
Eligibility criteria
- Inclusion Criteria :
- Post-Stroke Population:
- • Adult male or female
- • Patient who had a stroke more than 7 days ago
- • Patient hospitalized (in conventional hospitalization or day hospital) in the university neurological rehabilitation department of CHU de Nantes
- • Patient with voluntary motor function graded between 2 and 4 on the MRC (Medical Research Council) scale at the GM level
- • Patient classified between 3 and 8 on the New Functional Ambulation Classification
- Post-Spinal Cord Injury Population:
- • Adult male or female
- • Patient with an incomplete spinal cord injury classified as ASIA AIS C or D from level C2 to L5
- • Patient hospitalized (in conventional hospitalization or day hospital) in the neurological rehabilitation department of CHU de Nantes
- • Patient with voluntary motor function graded between 2 and 4 on the MRC (Medical Research Council) scale at the GM level
- • Patient classified between 3 and 8 on the New Functional Ambulation Classification
- Healthy Population:
- • • Adult male or female without any neurological disorders
- Exclusion Criteria :
- Post-Stroke and Post-Spinal Cord Injury Population:
- • Minor patient
- • History of calf surgery, surgery to reduce triceps surae spasticity, or intramuscular injection (e.g., botulinum toxin) in the plantar flexors within the last 6 months
- • Patient with a progressive condition contraindicating physical exertion (e.g., syrinx, cardiovascular instability)
- • Peripheral pathology of the considered lower limb
- Healthy Population:
- • History of calf surgery
- • History of muscle injury, fracture, or sprain of the lower limb within the last 3 months
- • History of neurological disorders
About Nantes University Hospital
Nantes University Hospital, a leading academic medical institution in France, is dedicated to advancing healthcare through innovative research and clinical trials. As a prominent sponsor of clinical studies, the hospital integrates cutting-edge scientific exploration with patient care, fostering collaborations among multidisciplinary teams of healthcare professionals and researchers. With a strong emphasis on ethical standards and patient safety, Nantes University Hospital aims to contribute to the development of effective therapies and interventions that enhance patient outcomes and overall public health.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Nantes, Loire Atlantique, France
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported