Postbiotic as Adjunct Treatment for Vaginal Candidiasis

Launched by MIN-TZE LIONG · Jun 19, 2024

Keywords

ClinConnect Summary

This clinical trial is studying the effectiveness of a treatment called postbiotic for women with vaginal candidiasis, which is a common yeast infection. The trial involves women who are sexually active and have been diagnosed with this condition, typically characterized by symptoms like a creamy whitish discharge and itching. Women aged between 18 and 45 who are willing to participate for four weeks may be eligible. However, certain women, such as those who are pregnant, have gone through menopause, or have had specific surgeries, cannot participate.

Participants in this study will receive either the postbiotic treatment or a placebo—a substance that looks the same but has no active ingredients—once a day for four weeks. The goal is to see if the postbiotic can help treat the infection more effectively than the placebo. Throughout the study, participants will be monitored to evaluate how well the treatment works and to ensure their safety. This trial is currently looking for volunteers, so if you think you might qualify, it could be a good opportunity to help advance research in treating vaginal candidiasis.

Gender

FEMALE

Eligibility criteria

• • Inclusion criteria
• • Women who are sexually active
• • Confirmed with candidiasis as confirmed via clinical observations which include creamy whitish vaginal discharge and vulva-vaginal itchiness
• • Willing to commit throughout the experiment
• • Exclusion criteria
• • Long term medication (6 months or more) for any illnesses
• • Pregnant
• • Menopaused
• • Uterus and/or cervix removed
• • Cervical intraepithelial neoplasia
• • Vaginal suppository treatments within 4-weeks prior to entering the study
• • Oral medication for vaginal illnesses or any vaginal therapy such as hormones and estrogen within 4-weeks prior to entering the study
• • Have used vaginal estrogen cream, ring or tablet within 4-weeks prior to entering the study
• • Have used vaginal moisturizers, lubricants or homeopathic preparations within 4-weeks prior to entering the study
• • Have used spermicide agent within 4-weeks prior to entering the study
• • Have pelvic or any gynecologic surgery 6-months prior to entering the study