The Avenues Study: Dual Use Cessation

Launched by UNIVERSITY OF WISCONSIN, MADISON · Jun 19, 2024

Keywords

ClinConnect Summary

The Avenues Study is a research trial designed to find the best way to help people who smoke cigarettes and use electronic cigarettes (often called vaping) to quit. The study will involve 500 participants who will be part of the trial for a year. Researchers are looking for adults aged 18 and older who smoke at least five cigarettes a day and have been vaping at least once a week for the past six months. Participants must be willing to set a quit date within the next 30 days and use specific medications like varenicline (a pill to help quit smoking) and nicotine patches.

If you decide to join the study, you can expect to receive support and guidance throughout the year as you work towards quitting smoking. It's important to know that participants will need to stop using certain medications for smoking cessation during the trial. The study is currently recruiting, so if you or someone you know fits the eligibility criteria and is interested in quitting smoking, this could be a valuable opportunity to get help.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Able to read and communicate in English
• • Willing to set a quit date to quit smoking cigarettes in the next 30 days
• • Willing and medically able to use varenicline and nicotine patches
• • Smoking ≥ 5 cigarettes per day for the past 6 months
• • Vaping weekly for at least 6 months
• • Willing to stop using nicotine replacement or varenicline
• • Willing to stop using bupropion (i.e., Wellbutrin, Zyban) if they are currently using it only for smoking cessation
• Exclusion Criteria:
• • Plans to move out of the area for the next 12 months
• • Currently in treatment for psychosis or bipolar disorder
• • If they are currently taking bupropion for non-smoking cessation reasons (e.g., Wellbutrin for depression)
• • Currently pregnant or breastfeeding. If a participant becomes pregnant while in the study, they will be allowed to continue in the study but will no longer receive study medications. They will also be asked to return any unused study medications.