Tissue Oximetry's Measurement in Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy
Launched by FONDAZIONE POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI IRCCS · Jun 20, 2024
Trial Information
Current as of July 24, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how well a special measurement called tissue oximetry can help doctors understand oxygen levels in muscle tissue during a specific type of surgery for ovarian cancer. The surgery, known as cytoreductive surgery, is combined with a treatment called hyperthermic intraperitoneal chemotherapy (HIPEC), which involves delivering heated chemotherapy directly into the abdominal cavity. The researchers want to find out if low oxygen levels in the muscle during the surgery could be linked to kidney problems afterward.
To participate in this trial, women aged 18 to 74 who are scheduled for cytoreductive surgery for ovarian cancer with HIPEC may be eligible. Participants can expect to have their muscle oxygen levels monitored during the surgery. This study aims to gather important information that could help improve patient care and outcomes in future ovarian cancer surgeries.
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • American Society Anesthesiologists (ASA) Classification 1-2
- • Cytoreductive surgery for ovarian cancer with laparoscopic or laparotomic technique with Hypertermic Intraperitoneal Chemotherapy.
- Exclusion Criteria:
- • Age \< 18 years
- • ASA \> or = 3
- • Cytoreductive surgery without hyperthermic intraperitoneal chemotherapy
About Fondazione Policlinico Universitario Agostino Gemelli Irccs
Fondazione Policlinico Universitario Agostino Gemelli IRCCS is a leading research and healthcare institution based in Rome, Italy, renowned for its commitment to advancing medical science and improving patient care. As a prominent academic medical center affiliated with the Catholic University of the Sacred Heart, it integrates clinical practice, education, and research, fostering innovation in various fields of medicine. The foundation conducts a wide range of clinical trials aimed at developing new therapies and enhancing treatment protocols, with a focus on translational research that bridges the gap between laboratory discoveries and patient care. Its multidisciplinary approach and dedication to high ethical standards position it as a key player in the landscape of clinical research and healthcare improvement in Italy and beyond.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Rome, , Italy
Patients applied
Trial Officials
Stefano Catarci, MD
Principal Investigator
FPG IRCCS
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported