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Search / Trial NCT06475261

Tissue Oximetry's Measurement in Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy

Launched by FONDAZIONE POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI IRCCS · Jun 20, 2024

Trial Information

Current as of July 23, 2025

Recruiting

Keywords

Tissue Oximetry Hyperthermic Intraperitoneal Chemotherapy Acute Kidney Injury Hemodynamics Parameters

ClinConnect Summary

This clinical trial is studying how well a special measurement called tissue oximetry can help doctors understand oxygen levels in muscle tissue during a specific type of surgery for ovarian cancer. The surgery, known as cytoreductive surgery, is combined with a treatment called hyperthermic intraperitoneal chemotherapy (HIPEC), which involves delivering heated chemotherapy directly into the abdominal cavity. The researchers want to find out if low oxygen levels in the muscle during the surgery could be linked to kidney problems afterward.

To participate in this trial, women aged 18 to 74 who are scheduled for cytoreductive surgery for ovarian cancer with HIPEC may be eligible. Participants can expect to have their muscle oxygen levels monitored during the surgery. This study aims to gather important information that could help improve patient care and outcomes in future ovarian cancer surgeries.

Gender

FEMALE

Eligibility criteria

  • Inclusion Criteria:
  • American Society Anesthesiologists (ASA) Classification 1-2
  • Cytoreductive surgery for ovarian cancer with laparoscopic or laparotomic technique with Hypertermic Intraperitoneal Chemotherapy.
  • Exclusion Criteria:
  • Age \< 18 years
  • ASA \> or = 3
  • Cytoreductive surgery without hyperthermic intraperitoneal chemotherapy

About Fondazione Policlinico Universitario Agostino Gemelli Irccs

Fondazione Policlinico Universitario Agostino Gemelli IRCCS is a leading research and healthcare institution based in Rome, Italy, renowned for its commitment to advancing medical science and improving patient care. As a prominent academic medical center affiliated with the Catholic University of the Sacred Heart, it integrates clinical practice, education, and research, fostering innovation in various fields of medicine. The foundation conducts a wide range of clinical trials aimed at developing new therapies and enhancing treatment protocols, with a focus on translational research that bridges the gap between laboratory discoveries and patient care. Its multidisciplinary approach and dedication to high ethical standards position it as a key player in the landscape of clinical research and healthcare improvement in Italy and beyond.

Locations

Rome, , Italy

Patients applied

0 patients applied

Trial Officials

Stefano Catarci, MD

Principal Investigator

FPG IRCCS

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported