Risk Factors Affect Weight Loss Outcomes After Treatment (WRRFA).

Launched by E-DA HOSPITAL · Jun 28, 2024

Keywords

ClinConnect Summary

The clinical trial, titled "Risk Factors Affect Weight Loss Outcomes After Treatment" (WRRFA), is exploring the reasons why some people struggle to maintain their weight loss after treatment for obesity. While treatments like weight loss medications and bariatric surgery can be effective, many patients still experience weight regain due to various factors, including eating habits, physical activity, and mental health. The study aims to identify these risk factors using different questionnaires that assess lifestyle, quality of life, food addiction, and emotional well-being. Ultimately, the goal is to create a helpful tool to better manage weight control in the future.

To be eligible for this study, participants must be between 20 and 65 years old and have a body mass index (BMI) of 30 or higher, which indicates obesity. They should have tried some form of diet or exercise in the past and must be able to communicate clearly without any severe cognitive or psychiatric issues. However, individuals who have had bariatric surgery or certain medical conditions, like severe depression or active cancer, cannot participate. If you join the study, you will help researchers understand the challenges of weight loss maintenance and contribute to developing better strategies for managing weight long-term.

Gender

ALL

Eligibility criteria

• • Inclusion 1.65 ≥ Age ≥ 20 years-old. 2.BMI ≥ 30. 3.Once attempted exercise or dietary control. 4.No cognitive deficiency and clear communication. 5. No severe psychotic disorders were evaluated by the psychiatrist. (e.g. schizophrenia, bipolar disorder, or severe depression).
• • 6. Signing the informed consent form for clinical trials.
• • Exclusion
• • 1. Once underwent bariatric surgery.
• • 2. Once used the GLP-1 receptor agonist.
• • 3. Pregnancy or preparation for pregnancy.
• • 4. Once and presenting gastric cancer.
• • 5. Presenting the other cancer.
• • 6. The abnormal endocrine system causes diseases with obesity.
• • 7. Major organ abnormalities (e.g., kidney failure, liver failure, heart failure, etc.).
• • 8. Gastric ulcer, and severe gastroesophageal reflux.
• • 9. Severe psychiatric disorders (schizophrenia, severe bipolar disorder, and depression, etc.).
• • 10. Bulimia nervosa or anorexia nervosa.
• • 11. Drug and alcohol abuse.
• • 12. Helicobacter pylori is not for bariatric surgery.
• • 13. The following diseases or conditions preclude the use of Contrave: 1)Uncontrolled hypertension, 2) History or current diagnosis of epilepsy, 3) Allergy to this medication, 4) Medications evaluated by a physician to interact with this drug (antidepressants, antipsychotics, liver medications, heart medications).
• • 14. The following diseases or conditions preclude the use of GLP-1 medication: 1) History or current diagnosis of medullary thyroid carcinoma, 2)History or current diagnosis of Multiple Endocrine Neoplasia syndrome type 2, 3)Allergy to this medication, 4)Medications evaluated by a physician to interact with this drug (antidepressants, antipsychotics, liver medications, heart medications).
• • 15. The following diseases or conditions preclude the use of Xenical medication: 1) History or current diagnosis of cholestasis, 2) Allergy to this medication, 3) Medications evaluated by a physician to interact with this drug (antidepressants, antipsychotics, liver medications, heart medications).