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Search / Trial NCT06482593

Periapical Healing in Response to Endodontically Treated Teeth With Different Sealing Cement

Launched by INSTITUCION UNIVERSITARIA COLEGIOS DE COLOMBIA · Jun 25, 2024

Trial Information

Current as of June 30, 2025

Active, not recruiting

Keywords

Clinical Trial Endodontic Sealer Periapical Healing

ClinConnect Summary

This clinical trial is looking at how different sealing materials used in root canal treatments affect the healing process of teeth that have had damage due to infection, known as apical periodontitis. The main goal is to compare three types of sealing cements to see which one helps the tooth heal better and faster after treatment. The researchers will use special imaging technology to measure the healing over a six-month period. They are particularly interested in whether a bioceramic sealer is more effective than other types of sealers.

To participate in this study, you need to be between 18 and 60 years old and healthy, meaning you don't have any serious medical conditions. You should require treatment for a single-rooted tooth that has infection and no symptoms at the time of your appointment. If you meet these criteria, you may be eligible to join the trial, which is currently ongoing but not recruiting new participants. After your treatment, you’ll need to have a permanent restoration done within 15 days. This study aims to provide valuable information that dentists can use to improve the care they provide to patients like you.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients aged 18 to 60
  • Patients systemically healthy (ASA I)
  • Patients that require endodontic therapy for single-rooted teeth with pulp necrosis and apical periodontitis (AP).
  • CBCT PAI periapical index score 3 or above, with no symptoms at the time of appointment.
  • Exclusion Criteria:
  • Exclusion criteria included other than ASA-1 classification
  • Patients with Perforated cortical plates at cbct analysis
  • Premature permanent teeth
  • Patients with Endodontic-periodontic lesions, dystrophic calcifications, more than 20° root curvature
  • Pregnancy or lactation
  • Root fracture cases
  • Use of analgesics within 12-24 hours root canal therapy and patients with endodontic abscess.

About Institucion Universitaria Colegios De Colombia

Institución Universitaria Colegios de Colombia is a prominent educational and research institution dedicated to advancing healthcare through innovative clinical trials and studies. With a strong emphasis on collaboration and academic excellence, the institution engages in cutting-edge research to improve patient outcomes and contribute to the medical community. Its commitment to ethical standards and rigorous scientific methodologies ensures that all clinical trials conducted under its auspices adhere to the highest quality and safety protocols, fostering advancements in health sciences and benefiting diverse populations.

Locations

Bogotá, Cundinamarca, Colombia

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported