Steroids for Rhinoplasty: Pain, Nausea, Edema and Ecchymosis

Launched by VANDERBILT UNIVERSITY MEDICAL CENTER · Jun 25, 2024

Keywords

ClinConnect Summary

This clinical trial is studying the effects of a medication called methylprednisolone, a type of steroid, on patients undergoing rhinoplasty, which is a surgery to reshape the nose. Researchers want to find out if taking this steroid can help reduce pain, nausea, swelling, and bruising after the surgery, as well as improve the overall experience for patients. While previous studies have shown that steroids can help with swelling and bruising, this trial aims to see if they can also make a difference in how much pain patients feel and how they feel overall after their surgery.

To be eligible for this study, participants must be at least 18 years old and planning to have their first rhinoplasty surgery without any other facial procedures or sinus surgeries happening at the same time. Unfortunately, people who have had previous nose surgeries, have certain medical conditions (like diabetes or liver problems), or are pregnant cannot take part in this study. If you join the trial, you can expect to be monitored for pain, nausea, and other symptoms after your surgery, helping doctors understand how effective the steroid treatment might be. This research is important because it could lead to better recovery experiences for future rhinoplasty patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adults at least 18 years of age who elect to undergo cosmetic or functional open primary rhinoplasty with/without osteotomies (repositioning the nasal bones)
• • No other facial plastics procedure nor sinus surgery performed simultaneously.
• Exclusion Criteria:
• • revision rhinoplasty
• • diabetic patients
• • patients with an allergy to steroids
• • use of PPE implants
• • parents receiving concurrent sinus surgery
• • patients receiving biologics or preop oral steroids
• • Patients that are pregnant or attempting to conceive
• • Liver failure or cirrhosis
• • Diagnosis of hypothyroidism
• • Diagnosis of glaucoma