Olive Leaf Extract, Meta-inflammation, Anxiety, and Excess Weight

Launched by UNIVERSITY OF GUADALAJARA · Jun 28, 2024

Keywords

ClinConnect Summary

A randomized double-blind placebo clinical trial is proposed. Study groups will be comprised of women living with excessive weight from the Guadalajara Metropolitan Area who meet the following criteria: age ≥18- ≤40 years, body mass index (BMI) ≥25- ≤40 kg/m\^2, blood pressure ≤ 129 mmHg systolic and ≤80 diastolic; anxiety symptomatology score 6 to 14 (mild) according to Hamilton Anxiety Scale (HAS).

70 women at the University Center for Health Sciences (CUCS) from Universidad de Guadalajara who meet inclusion criteria will be invited to participate. Two groups will be randomly formed cons...

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Females.
• • Residing in Guadalajara Metropolitan Area (GMA).
• • Initial age ≥18-≤ 40 years
• • Initial Body Mass Index (BMI) ≥25-≤40 kg/m\^2
• • Blood pressure: ≤129mmHg systolic and ≤80 diastolic.
• • Anxious symptomatology score 6 to 14 (mild) through the Hamilton Anxiety Scale (HAS).
• Exclusion Criteria:
• • Use of psychoactive drugs, suffering from major psychiatric disorders (depression, attention deficit hyperactivity disorder, bipolar disorder, eating disorders), pregnancy, breastfeeding, hypotension, alcohol use disorder (AUD).
• • Suffer from liver, kidney, or thyroid disease or cancer.
• • Olive allergy.
• • Consume any medication that influences weight
• • Consume some other type of food supplement from organic origin.
• • Less than 70% adherence frequency to the consumption of the extract/placebo.
• • Getting pregnant during the study.