Isotretinoin Versus Excimer Light an Adjuvant in Treating Onychomycosis

Launched by ZAGAZIG UNIVERSITY · Jul 2, 2024

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ClinConnect Summary

This clinical trial is looking at different ways to treat onychomycosis, which is a fungal infection of the nails. The researchers want to compare three treatment options: one group of patients will take a medication called itraconazole by itself, another group will take itraconazole along with a low dose of isotretinoin (a drug often used for acne), and the third group will use itraconazole together with excimer light therapy, which is a special type of light treatment. The goal is to see which combination works best for getting rid of the infection.

To participate in the trial, patients must have onychomycosis, but there are some important exclusions. For instance, pregnant or breastfeeding women, those taking certain cholesterol medications or drugs that make the skin sensitive to light, and individuals with specific health conditions like liver disease, heart disease, or diabetes are not eligible. If you qualify, you'll be assigned to one of the three treatment groups and will receive the corresponding therapy. The trial is currently not recruiting participants, but it's an opportunity for those who are eligible to explore new treatment options for this common nail infection.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • patients with onychomycosis
• Exclusion Criteria:
• • pregnant and lactating females patients on statin therapy or photosensitizing drugs patients with liver disease, heart disease and diabetes milletus.