ClinConnect ClinConnect Logo
Search / Trial NCT06487247

HEME Home Transfusion Program

Launched by DANA-FARBER CANCER INSTITUTE · Jul 2, 2024

Trial Information

Current as of June 26, 2025

Not yet recruiting

Keywords

Leukemia Myeloma Myelodysplastic Syndromes Hematologic Malignancy Hematologic Diseases Lymphoma

ClinConnect Summary

The HEME Home Transfusion Program is a research study designed to explore a new way of providing blood transfusions to patients with certain blood cancers, like leukemia and lymphoma, in the comfort of their own homes while they receive hospice care. The goal is to see if this home-based approach can improve patients' quality of life, mood, and the overall care they receive at the end of their lives compared to the usual methods of care.

To participate in this study, patients must be at least 18 years old, have a specific type of blood cancer that has come back or not responded to treatment, and have received care at a specific cancer center. They also need to have had at least one blood transfusion in the past without serious side effects. Caregivers of these patients can also take part if they are over 18. However, patients who are already in hospice care or living in a nursing home cannot join. If eligible, participants can expect to receive blood transfusions at home, which could help ease their symptoms and improve their overall experience during this challenging time.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria for Patient Participants:
  • Diagnosis of a relapsed/refractory hematologic malignancy
  • Age ≥ 18 years
  • Receipt of primary oncologic care at DFCI (at least 2 outpatient visits in 12 months prior to enrollment)
  • Has received at least one red blood cell (RBC) or platelet transfusion since blood cancer diagnosis in the clinic or hospital setting without a severe transfusion reaction
  • Patient resides within catchment served by Care Dimensions Hospice
  • Physician-estimated prognosis of six months or less
  • Inclusion Criteria for Caregivers:
  • Identified informal caregiver of enrolled patient with hematologic malignancy
  • Age ≥ 18 years
  • Exclusion Criteria for Patient Participants:
  • Age \< 18 years
  • Already enrolled in hospice
  • Resides in nursing home or assisted living facility
  • History of previous serious adverse transfusion reaction
  • Exclusion Criteria for Caregivers:
  • -Age \< 18 years

About Dana Farber Cancer Institute

The Dana-Farber Cancer Institute is a premier cancer research and treatment institution located in Boston, Massachusetts. Renowned for its commitment to advancing cancer care through innovative research, the institute integrates cutting-edge clinical trials with a multidisciplinary approach to patient care. With a focus on translating scientific discoveries into effective therapies, Dana-Farber collaborates with a network of leading researchers and healthcare professionals to improve outcomes for patients with cancer. The institute’s dedication to education, advocacy, and community engagement further underscores its mission to eradicate cancer and enhance the quality of life for those affected by the disease.

Locations

Boston, Massachusetts, United States

Boston, Massachusetts, United States

Patients applied

0 patients applied

Trial Officials

Oreofe Odejide, MD, MPH

Principal Investigator

Dana-Farber Cancer Institute

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported