The Peripheral Blood Multi-Omics Study on Sleep Loss

Launched by FIRST AFFILIATED HOSPITAL OF ZHEJIANG UNIVERSITY · Jul 1, 2024

Keywords

ClinConnect Summary

The Peripheral Blood Multi-Omics Study on Sleep Loss is a research project that is looking into how lack of sleep affects people of different ages and cognitive abilities. The study focuses on understanding the connection between sleep deprivation, aging, and diseases like Alzheimer’s. Researchers want to learn more about the changes that happen in the body when we don’t get enough sleep, and how these changes might relate to memory and thinking skills. By examining blood samples, they hope to uncover important information about how sleep loss impacts our health, especially as we age.

To participate in this study, individuals between the ages of 65 and 74 or 29 and 219 years old can apply, as long as they can provide informed consent and meet specific criteria. However, those with certain medical or psychological conditions, such as serious mental health issues or severe illnesses, may not be eligible. Participants will be asked to follow study procedures and will contribute to important research that could help improve our understanding of sleep and its effects on health.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Signed informed consent form；
• • 2. Meet the inclusion criteria for each arms.
• Exclusion Criteria:
• • 1. Failure to provide informed consent;
• • 2. Inability to follow study procedures due to issues such as language barriers or cognitive impairment;
• • 3. Regular use of medications that may alter the relationship between sleep and outcome variables (e.g., opioid medications, benzodiazepines, and Z drugs \[non-benzodiazepine hypnotics\]);
• • 4. History of alcohol abuse, substance abuse, consciousness disorders, cerebrovascular disease, head injury, epilepsy, encephalitis, or other neurological disorders;
• • 5. Diagnosis of schizophrenia, severe depression, anxiety disorders, or other severe psychiatric conditions;
• • 6. Presence of severe arrhythmias, myocardial infarction within the last 6 months, severe pulmonary dysfunction, renal or hepatic insufficiency, severe anemia, severe gastrointestinal diseases, tumors, or other severe medical conditions.