Personal BP - CAI Study

Launched by EDWARDS LIFESCIENCES · Jul 1, 2024

Keywords

ClinConnect Summary

The Personal BP - CAI Study is a research trial designed to explore how to better set personalized blood pressure targets for patients undergoing planned heart surgery. The study aims to use a special tool called the Cerebral Adaptive Index to help doctors understand which blood pressure levels are safest for each patient, especially those at higher risk for issues related to blood flow to the brain.

To participate in this study, you need to be at least 45 years old and scheduled for cardiac surgery that involves a technique called Cardiopulmonary Bypass. You should also have a history of high blood pressure or other conditions that increase your risk for brain-related health issues, like diabetes or previous strokes. If you join, you will be monitored closely during your surgery using advanced equipment to keep track of your blood pressure. The study is currently looking for participants, and it is important that you can understand English, are not pregnant, and are not having surgery for a congenital heart defect. Your involvement could help improve how doctors manage blood pressure during surgery for future patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Signed informed consent
• • 2. Age ≥ 45 years
• • 3. Planned cardiac surgery with Cardiopulmonary Bypass (CPB)
• • 4. Planned monitoring with ForeSight sensor and HemoSphere monitor
• • 5. Planned arterial catheterization for blood pressure monitoring
• • 6. High risk for cerebral vascular disease, defined as: a history of hypertension, pulse pressure \> 60 mmHg, diabetes, stroke, transient ischemic attack, carotid bruit, tobacco smoking, or peripheral vascular disease
• Exclusion Criteria:
• • 1. Non-English speaking
• • 2. Confirmed to be pregnant
• • 3. Surgery for congenital heart defect
• • 4. Non-availability of HemoSphere with laptop CAI interface