Efficacy of Formulated Eggshell Derived Nano-hydroxyapatite Containing Toothpaste With and Without Addition of Fluoride vs. Conventional Desensitizing Fluoride Containing Toothpaste in Management of Dentin Hypersensitivity

Launched by CAIRO UNIVERSITY · Jul 6, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at different types of toothpaste to help people who experience dentin hypersensitivity, which is a painful sensitivity in the teeth. Specifically, it will compare a special toothpaste made from eggshells that contains nano-hydroxyapatite (a compound that helps to strengthen teeth) both with and without fluoride, against a conventional desensitizing fluoride toothpaste. The goal is to see which toothpaste works best in blocking the tiny holes in teeth (called dentinal tubules) and improving tooth health.

To participate in this study, individuals must be between 18 and 60 years old and have good oral hygiene. They should also have noticeable tooth sensitivity, indicated by a pain level of 5 or higher on a scale. However, there are some exclusions; for example, those with allergies to the toothpaste ingredients or certain dental issues may not qualify. If eligible, participants can expect to use the toothpaste and have their tooth sensitivity evaluated, helping researchers understand the effectiveness of these new formulations in managing tooth sensitivity.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adult Patients Aged 18-60
• • Males or females.
• • Good oral hygiene
• • Absence of abnormal occlusion habits (e.g. bruxism, nail biting, tooth clenching and mouth breathing).
• • Teeth with hypersensitivity, VAS ≥5
• • Co-operative patients who show interest to participate in the study.
• Exclusion Criteria:
• • Patients with known allergic or adverse reaction to the tested materials.
• • Systematic disease that may affect participation.
• • Xerostomic patients.
• • Patients with bad oral hygiene
• • Patients with orthodontic appliances, or bridge work that might interfere with evaluation
• • Patients who did any periodontal surgeries within the previous 6 months.
• • Patients with physical disabilities