Clinical Efficiency of Bioactive Pit and Fissure Sealant
Launched by CAIRO UNIVERSITY · Jul 2, 2024
Trial Information
Current as of July 09, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at two types of sealants designed to protect the chewing surfaces of back teeth, known as molars, from cavities. One sealant is a new bioactive resin, and the other is a traditional fluoride-releasing resin. The study will help determine which sealant works better in preventing cavities when applied to teeth that are at high risk but currently have no signs of decay.
To participate in this trial, you need to be between 6 and 10 years old and have certain teeth that are fully erupted and show no signs of cavities. You should also be able to cooperate and follow instructions and have good oral hygiene. Unfortunately, if you have certain health issues, allergies to specific materials, or severe dental problems, you may not be eligible to join. If you are chosen to participate, you can expect to have your teeth assessed using simple visual checks and a special camera. This study aims to improve dental care for children at risk of developing cavities.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- * Inclusion Criteria of participants:
- • Patients with caries susceptible fiss- ures in fully erupted first permanent molars showing nosigns of caries.
- • Co-operative patients approving to part- icipate in the trial.
- • Good oral hygiene.
- * Inclusion Criteria of teeth:
- • Caries susceptible occlusal pits and fissures.
- • Intact contact with opposing teeth.
- • Teeth with no previous restorations in other surfaces.
- Exclusion Criteria:
- * Exclusion criteria of participants:
- • patients with Disabilities, systemic disease or severe medical complications.
- • patients have allergic history concerning methacrylate.
- • patients with rampant caries, xerostomia, evidence of severe bruxism, clenching, or tempromandibular joint disorders
- • participants who show lack of compliance.
- * Exclusion criteria of teeth:
- • Carious pits and fissures.
- • Developmental tooth defect.
- • Partially erupted teeth
- • Periapical pathology or signs of pulpal pathology.
- • Tooth hypersensitivity.
- • Heavy occlusion and occlusal contacts.
About Cairo University
Cairo University, a premier institution in Egypt, is dedicated to advancing medical research and education through innovative clinical trials. With a strong emphasis on improving healthcare outcomes, the university collaborates with various stakeholders to conduct rigorous scientific studies that address critical health challenges. Leveraging its extensive resources and expert faculty, Cairo University aims to contribute valuable insights to the medical community and enhance patient care both locally and globally. Through its commitment to ethical research practices and excellence, the university plays a pivotal role in shaping the future of healthcare in the region.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported