Dynamic Hormone Profiling and Multimodal Data Capture in Primary Aldosteronism

Launched by HAUKELAND UNIVERSITY HOSPITAL · Jul 3, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a condition called Primary Aldosteronism (PA), which involves an excess of certain hormones that can affect blood pressure and other body functions. The researchers are using a special method called 24-hour microdialysis to closely examine hormone levels in patients suspected of having PA. Alongside hormone monitoring, they will also track things like blood pressure, sleep patterns, activity levels, and food intake to gather comprehensive information about the participants' health. The goal is to create a new, easy-to-use test that can diagnose PA more quickly and accurately.

To participate in the study, individuals must be aged between 18 and 70 and either suspected of having PA or already diagnosed with it based on specific medical guidelines. Important to note is that those who are pregnant, have adrenal failure, or are taking certain medications might not be eligible. Participants will have the opportunity to contribute to important research that could improve how PA is diagnosed and managed in the future.

Gender

ALL

Eligibility criteria

• • Inclusion criteria Age 18 to 70 years Suspected PA admitted for diagnostic saline infusion testing or confirmed PA diagnosis according to Endocrine Society criteria.. Written informed consent
• • Exclusion criteria
• • Age \<18 or \> 70 years.
• • Pregnancy.
• • Known adrenal failure and/or on steroid therapy (oral, inhaled, parenteral or topical) or other interfering medication.