Management of Postspinal Anesthesia Hypotension During Elective Cesarean Section: Baby Norepinephrine Versus Ephedrine

Launched by HOPITAL CHARLES NICOLLE · Jul 4, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how to manage low blood pressure (hypotension) that can occur after spinal anesthesia during elective cesarean sections. Researchers want to compare two treatments: diluted norepinephrine and ephedrine. Both are medications used to help raise blood pressure, but norepinephrine may have fewer side effects for mothers and their babies. The goal is to find out which treatment works better in keeping blood pressure stable during and after the surgery.

To participate in this study, women aged 18 to 38 who are having a planned cesarean section under spinal anesthesia may be eligible. Participants will be randomly assigned to receive either norepinephrine or ephedrine after their anesthesia is given. Throughout the procedure, their blood pressure and heart rate will be closely monitored, and any side effects will be recorded. This study aims to improve the safety of cesarean sections for both mothers and their newborns.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Singleton full-term consenting pregnant females of ASA grade II, aged 18-38 years, scheduled for elective cesarean section under spinal anesthesia
• Exclusion Criteria:
• • Any parturient falling in the category ASA grade III and IV, contrindications to spinal anesthesia, preeclampsia, chronic hypertension, comorbidity with diabetes mellitus, cardiovascular disorders and psychiatric illness are non included.
• • They are excluded the case of failure of spinal anesthesia, conversion to general anesthesia, post-partum bleeding, and failure to follow protocol.