Patient Controlled Administration of Liquid Acetaminophen

Launched by YALE UNIVERSITY · Jul 5, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at a new way for patients to manage their pain after shoulder surgery by using a method called patient-controlled administration of liquid acetaminophen, which is a common and safe medication for pain relief. The goal of the study is to see if patients find it easy and acceptable to take their own doses of this medicine while they are in the hospital. The trial is currently recruiting participants who are adults over 18 years old and are scheduled for total shoulder or reverse total shoulder surgery.

To join the study, participants must be able to swallow liquid medication and not have certain health issues, such as chronic pain, a history of substance abuse, or liver problems. During the trial, patients will have the chance to manage their own pain relief while nurses will help administer the medication. This study is important because it could lead to better ways for patients to control their pain after surgery, making their recovery more comfortable.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Participants
• • Adult patients older than 18 years old admitted to SRC for total shoulder and reverse total shoulder arthroplasty
• • Nurses
• • The nurse who will administer acetaminophen to a study patient.
• Exclusion Criteria:
• • Participants
• • Pregnant patient
• • Patients that cannot swallow pills or cannot take liquid (for example due to risk of aspiration)
• • Emergency surgery
• • Chronic pain
• • On home opioids, any other pain modulating medications including benzodiazepine, Neurontin, ketamine.
• • Past medical or social history of substance abuse disorder, including ethanol misuse disorder, marijuana misuse disorder
• • History of any psychiatric disorders including anxiety, depression, any cognitive dysfunction
• • Any patients who cannot provide informed consents on their own (those who would need Legally Authorized Representatives (LARs) or surrogates)
• • Liver dysfunction limiting amount of safe oral acetaminophen
• • baseline hyperbilirubinemia (ex: chronic liver disease, Gilbert's)
• • patients unable to take PO
• • Patients with neurologic, neuromuscular, or movement disorders unable to drink from a cup.
• • Nurses
• • any nurse who is not involved in the direct care of a study patient, or who is not comfortable with setting up the PCA pump.