MBC Physical Activity Study

Launched by THOMAS JEFFERSON UNIVERSITY · Jul 8, 2024

Keywords

ClinConnect Summary

The MBC Physical Activity Study is a clinical trial that looks at how a customized exercise program can help women with metastatic breast cancer—meaning the cancer has spread to other parts of the body. The goal is to see if this tailored physical activity can improve patients' overall fitness, quality of life, and reduce feelings of fatigue. The program is designed by a qualified cancer exercise specialist and provides individual assessments to ensure that each participant receives the right level of exercise that suits their abilities.

To be eligible for this study, participants must be female, at least 18 years old, and diagnosed with metastatic breast cancer within the last five years. They should have a performance status that allows them to engage in some physical activity and should not be currently active at recommended levels. Participants will need access to a smart device and Wi-Fi to join the virtual exercise sessions. Throughout the study, participants can expect support and guidance in following their personalized exercise plans, all while being closely monitored to ensure their safety and comfort.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Female
• • Aged 18 and older
• • Able to read and speak English
• • Diagnosed with metastatic breast cancer within 60 months of study enrollment
• • Performance status Eastern Cooperative Oncology Group (ECOG) 0-2
• • Insufficiently inactive defined as answer "no" to screening question "On average, do you engage in at least 75 minutes a week of vigorous activity (like jogging) or at least 150 minutes a week of moderate activity (like a brisk walk)?"
• • Able to comprehend and sign a written informed consent (no cognitive decline)
• • Willing to comply with all study procedures and be available for the duration of the study through at least week 2 of 2Unstoppable
• • Medically cleared by co-investigator or principal investigator (PI) to engage in aerobic and resistance exercise intervention
• • Access to a smart device and have an active wi-fi connection at home
• Exclusion Criteria:
• • Severe or unstable cardiopulmonary, metabolic, or renal disease
• • Unable to walk safely without physical assistance of another person or assistive device
• • Any condition that may limit the ability to comply with behavioral and physical recommendations of the virtual exercise program
• • Pregnancy