AUTOANTIBODIES AND SYSTEMIC SCLEROSIS
Launched by IRCCS OSPEDALE SAN RAFFAELE · Jul 9, 2024
Trial Information
Current as of November 10, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is studying a condition called Systemic Sclerosis (SSc), which is an autoimmune disease that can cause skin and internal organ changes. The research aims to better understand how specific antibodies in the blood affect the disease and how a medication called Efgartigimod might help. The trial will use advanced laboratory tests to look at how cells behave when exposed to these antibodies and the potential benefits of the treatment. Researchers will investigate whether Efgartigimod can prevent or improve changes in blood vessel and cell function related to SSc.
To participate in this study, individuals must have positive autoantibodies related to SSc and be between the ages of 65 and 92. Unfortunately, pregnant individuals cannot join the trial. While the study is not yet recruiting participants, those who take part can expect to contribute to important research that may lead to new insights and treatment approaches for SSc. As the study progresses, researchers hope to uncover valuable information that could guide future therapies.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • positivity of autoantibodies
- Exclusion Criteria:
- • pregnant
About Irccs Ospedale San Raffaele
IRCCS Ospedale San Raffaele is a leading research hospital and clinical trial sponsor based in Milan, Italy, renowned for its commitment to advancing medical knowledge and improving patient care through innovative research. As an IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico), it integrates clinical practice with cutting-edge scientific research, focusing on a wide range of therapeutic areas including oncology, neurology, and cardiovascular diseases. The institution is dedicated to conducting high-quality clinical trials that adhere to rigorous ethical standards, fostering collaboration among multidisciplinary teams to translate scientific discoveries into effective treatments for patients. Through its robust infrastructure and expertise, IRCCS Ospedale San Raffaele plays a pivotal role in shaping the future of healthcare both nationally and internationally.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported