Early Diagnosis of Acute Renal Failure by Urine Trehalase Levels.

Launched by ISTINYE UNIVERSITY · Jul 11, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a new way to detect acute kidney injury (AKI) in patients undergoing surgery. The researchers believe that by measuring a substance called trehalase in urine, they can identify kidney problems early, especially in patients who might be at risk due to low blood pressure during surgery. Detecting these issues early could help doctors treat the problem quickly and prevent further complications after the operation.

To participate in this study, patients need to be between the ages of 18 and 65 and have no history of kidney problems or certain health conditions that may complicate surgery. Participants will be asked to sign a consent form and will undergo some tests to ensure their kidney function is normal before surgery. This trial is not yet recruiting participants, but it aims to improve the way we monitor kidney health during surgical procedures, which could lead to better outcomes for patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Being over the age of 18 and under the age of 65
• • Having signed the BGOF form to be included in the study,
• • Being in ASA 1 or ASA 2 classification
• • Not having kidney failure or kidney disease
• • No history of single kidney or renal transplantation
• • Not using nephrotoxic drugs or agents before surgery
• • Renal function tests taken preoperatively should be within normal ranges.
• • No urinary tract infection or urinary problems (such as polyuria, oliguria or anuria)
• Exclusion Criteria:
• • Those under the age of 18 or over the age of 65
• • Those who do not want to participate in the study
• • ASA 3 and above
• • Having previously received treatment for kidney disease - including kidney stones -
• • Having been previously diagnosed with acute or chronic renal failure
• • Having a single kidney or a history of renal transplantation
• • Using nephrotoxic drugs or agents (such as contrast material) before surgery
• • Kidney function tests taken preoperatively are not within normal ranges
• • Having a urinary tract infection or urinary problem (such as polyuria, oliguria or anuria)
• • Having a history of kidney stones, acute renal failure or chronic renal failure
• • Those with active infection or disease before surgery
• • They were determined as patients for whom consent was not obtained for the study.