Genetic and Epigenetic Background of Inner Ear Dysfunction in Turner Syndrome

Launched by GØDSTRUP HOSPITAL · Jul 16, 2024

Keywords

ClinConnect Summary

This clinical trial is studying the connection between genetics and hearing loss in people with Turner Syndrome (TS), a condition that affects females and can lead to various health issues, including problems with hearing. The researchers want to discover if there are specific patterns in DNA and gene activity that could explain why some individuals with TS experience sensorineural hearing loss (SNHL). They hope this research will lead to new treatments that could help delay or replace the need for hearing aids.

To participate in the trial, individuals must be between 18 and 50 years old and must not have any serious medical or mental health conditions that could affect their inner ear function. During the study, participants will undergo several tests, including ear and hearing examinations, balance tests, blood tests, and scans of the inner ear. This research could provide important insights into the underlying causes of hearing loss and help improve the care for those with Turner Syndrome.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • age between 18 and 60 years old
• Exclusion Criteria:
• • Contraindications for the MRI or CBCT
• • Serious medical disorders
• • Neurological or psychiatric disorders of any kind
• • Use of medication that is known to influence inner ear function
• • Medical history with dizziness or hearing problems (controls only)