Additive Effects of Clonidine Used in Propofol Sedation in Colonoscopy

Launched by TANTA UNIVERSITY · Jul 17, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how adding a medication called clonidine to propofol sedation affects patients undergoing a colonoscopy. The main goal is to see if using clonidine makes the sedation safer, increases patient satisfaction, and improves the overall efficiency of the procedure.

To participate in this trial, you need to be between 18 and 65 years old and in generally good health. This means you should be classified as ASA physical status I or II, which indicates a low risk for anesthesia complications. However, if you have had a colonoscopy recently, had surgery on your colon, or have serious heart issues, you wouldn't qualify for this study. If you join, you can expect to receive either propofol alone or propofol with clonidine during your colonoscopy, and your experiences will help researchers understand the benefits of this combination.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age 18-65 years.
• • Both sexes.
• • American Society of Anesthesiology (ASA) physical status I-II.
• • Patients undergoing colonoscopy.
• Exclusion Criteria:
• • Patients had recent history of colonoscopy.
• • Previous colonic resection.
• • Severe heart failure (ejection fraction \< 30%).
• • Known history of hypersensitivity to propofol or clonidine and any need for anesthetic drug administration other than the study protocol.