Effect of Calcium Hypochlorite Versus Sodium Hypochlorite as Root Canal Irrigants on Postoperative Pain and Bacterial Reduction in Mandibular Premolars With Necrotic Pulps. .

Launched by CAIRO UNIVERSITY · Jul 13, 2024

Keywords

ClinConnect Summary

This clinical trial is looking to compare two different substances, Calcium Hypochlorite and Sodium Hypochlorite, used during root canal treatments to see which one is better at reducing pain after the procedure and eliminating bacteria in certain teeth. The study will focus on patients with specific types of mandibular premolar teeth that have a condition called pulp necrosis, which means the nerve inside the tooth is dead but isn't causing any pain.

To participate in this trial, you need to be a healthy adult between the ages of 20 and 55 and have a specific type of tooth problem. Some conditions, such as significant health issues or certain dental problems, would exclude you from taking part. If you join the study, you can expect to receive one of the two treatments during your root canal procedure, and your pain levels and bacteria counts will be monitored afterward. The trial is not yet recruiting participants, but it aims to provide valuable information on how to improve root canal treatments for patients in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Systematically healthy patient (ASA I, II).
• • 2. Age between 20 and 55 years
• • 3. Male or female.
• • 4. Mandibular premolar teeth having single canals diagnosed with pulp necrosis with asymptomatic apical periodontitis.
• • 5. Radiographic examination using Digora intraoral periapical sensor plate and software showing mandibular premolars with (0-2 mm) periapical radiolucency.
• Exclusion Criteria:
• • 1. Medically compromised patients having significant systemic disorders. (ASA III or IV).
• • 2. History of intolerance to NSAIDS.
• 3. Teeth with:
• • Immature roots
• • Vital pulp tissues.
• • Association with swelling.
• • Acute peri-apical abscess or acute exacerbation of a chronic abscess.
• • Mobility Grade II or III.
• • Previously accessed or endodontically treated
• • Deep periodontal pockets more than 4 mm
• • Vertical root fractures, coronal perforation, calcification, and external or internal root resorptions.
• • 4. Patients who could not interpret the NRS.
• • 5. Patients with diabetes, immune-compromising, and immunosuppression disease and pregnant women were, also, excluded.