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Search / Trial NCT06509776

Skeletal Maturation and Endocrine Health in Young Adults

Launched by HOLBAEK SYGEHUS · Jul 15, 2024

Trial Information

Current as of August 21, 2025

Enrolling by invitation

Keywords

Bone And Bones Bone Mineralization Bone Mineral Density Bone Density Endocrinology Hormones Thyroid Hormones Parathyroid Hormone Puberty Adolescent Glucocorticoids Genetics Human Genetics Epigenomics Neonatal Screening Body Composition Cohort Study Epidemiology Phenotype

ClinConnect Summary

Population-based, nationwide, cross-sectional, clinical study with already available early life exposure data including bio banked neonatal biological samples. An embedded design using the full 2006+2007 birth cohorts is used to demonstrate external validity of the clinically assessed cohort. We will obtain the necessary ethics and regulatory approval and individual consent from the participants who are all aged 18.

The overall aim of the project addresses whether the following sets of potential determinants are associated with young adult hormonal status, lipids, bone turnover markers, bo...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Individuals (n = 2000) born in Denmark in 2006 or 2007
  • Are 18 years old and alive at the time of the clinical examination
  • Exclusion Criteria:
  • Pregnancy or lactation
  • No DBS samples available
  • Lack of consent to use DBS samples or national health registries
  • Emigration or disappearance

About Holbaek Sygehus

Holbæk Sygehus, a leading healthcare institution in Denmark, is dedicated to advancing medical research and improving patient outcomes through innovative clinical trials. With a strong emphasis on collaboration and ethical practice, the hospital provides a robust infrastructure for conducting a diverse range of studies across various therapeutic areas. Holbæk Sygehus is committed to fostering a patient-centered approach, ensuring that clinical trials not only contribute to scientific knowledge but also prioritize safety and well-being. Through its experienced research team and state-of-the-art facilities, Holbæk Sygehus plays a pivotal role in the development of new therapies and enhancements in clinical care.

Locations

Aalborg, , Denmark

Aarhus, , Denmark

Copenhagen, , Denmark

Frederiksberg, , Denmark

Holbæk, , Denmark

Hvidovre, , Denmark

Køge, , Denmark

Odense, , Denmark

Odense, , Denmark

Patients applied

0 patients applied

Trial Officials

Bo Abrahamsen, MD, PhD

Study Chair

OPEN, University of Southern Denmark, Odense and Department of Medicine 1, Holbæk Hospital, Holbæk

Katrine H Rubin, MHS, PhD

Principal Investigator

OPEN, Department of Clinical Research, University of Southern Denmark and Odense University Hospital

Bente Langdahl, MD, PhD

Principal Investigator

Department of Clinical Medicine and Department of Endocrinology and Diabetes, Aarhus University

Peter Vestergaard, MD, PhD

Principal Investigator

Faculty of Medicine, Aalborg University and Department of Endocrinology, Aalborg University Hospital

Berit L Heitmann, DMD, PhD

Principal Investigator

The Parker Institute, Frederiksberg Hospital, Frederiksberg

Mina N Händel, Msc, PhD

Principal Investigator

The Parker Institute, Frederiksberg Hospital, Frederiksberg

Charlotte L Tofteng, MD, PhD

Principal Investigator

Department of CIinical Medicine, Endocrinology, Zealand University Hospital, Køge

Pernille Bach-Mortensen, MD, PhD

Principal Investigator

Department of Endocrinology, Amager and Hvidovre Hospital, Hvidovre

Pernille Hermann, MD, PhD

Principal Investigator

Department of Endocrinology, Odense University Hospital, Odense

Niklas R Jørgensen, MD, PhD

Principal Investigator

Department of Clinical Biochemistry and Centre of Diagnostic Investigation,Rigshospitalet Copenhagen

Jonas Bybjerg-Grauholm, MSE

Principal Investigator

Danish Center for Neonatal Screening, Statens Serum Institut, Copenhagen

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported