Intraosseous Morphine Administration During Anterior Cruciate Ligament Reconstruction

Launched by THE METHODIST HOSPITAL RESEARCH INSTITUTE · Jul 15, 2024

Keywords

ClinConnect Summary

This clinical trial is investigating whether a method of giving morphine directly into the bone can help reduce pain and the need for other pain medications after surgery for a torn anterior cruciate ligament (ACL). The study is specifically looking at patients who are having a particular type of ACL reconstruction surgery using their own bone tissue.

To be eligible for this trial, participants need to be between 18 and 40 years old and undergoing this specific ACL surgery. Unfortunately, if someone is outside this age range, has a history of substance abuse, or is allergic to morphine, they won't be able to participate. Those who do join the study can expect to receive either the bone-injected morphine or standard pain management, and their pain levels and medication use will be monitored after their surgery. This trial is currently recruiting participants and aims to find better ways to manage pain for people recovering from ACL injuries.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients of the IRB approved surgeon(s) undergoing ACL reconstruction with bone-to-bone (BTB) autograft
• • Patients aged between 18-40 years old at the time of surgery
• Exclusion Criteria:
• • Patients undergoing ACL reconstruction with any other type of autograft or allograft other than BTB
• • Patients younger than 18 years old or older than 40 years old
• • Patients undergoing meniscal root repair or any other repair that changes their weight-bearing status
• • Patients with a history of substance abuse
• • Vulnerable populations
• • Patients on chronic pain medication within the last 6 months
• • BMI \>/= 35
• • Allergy to morphine
• • Unwilling to participate
• • Any additional reason the PI deems reasonable