Vulnerability and Risk of Neuropathic Pain in Cancer

Launched by UNIVERSITY HOSPITAL, CLERMONT-FERRAND · Jul 15, 2024

Keywords

ClinConnect Summary

This clinical trial is studying the challenges of neuropathic pain in cancer patients. Neuropathic pain is a type of pain that can occur after cancer treatments like surgery, chemotherapy, or radiation. Many cancer patients experience this chronic pain, which can affect their quality of life and can be difficult to treat. The trial aims to understand the factors that contribute to this pain, such as previous pain experiences, emotional state, and social circumstances, to better predict who might be at risk for developing ongoing pain after their cancer treatment.

To participate in this study, you must be over 18 years old and currently undergoing treatment for certain types of cancer, such as breast, gynecological, colorectal, or lung cancer. You need to be able to understand and follow the study's requirements and agree to participate. If you join the trial, you’ll help researchers learn more about how to recognize and predict chronic pain in cancer patients, which could lead to improved care and support for future patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria Patients:
• • Patient over 18 years of age,
• • Patient suffering from cancer (breast, gynecological, colorectal, lung) and having to undergo one or more anti-cancer therapeutic procedures (chemotherapy, surgery, hormonal therapy, radiotherapy, targeted therapy, etc.),
• • Sufficient cooperation and understanding to comply with the study requirements,
• • Agreement to give oral consent for the study,
• • Affiliation with the French Social Security system.
• Exclusion Criteria Patients:
• • History of cancer and anti-cancer therapy (surgery, chemotherapy, radiotherapy, hormone therapy, targeted therapy, etc.),
• • History and/or presence of primary brain tumors (glioblastoma, meningioma, neurofibroma, etc.) ),
• • History of neurological disorders (Parkinson's disease, Alzheimer's disease, dementia, epilepsy, moderate to severe head trauma, etc.),
• • Medical and/or surgical history judged by the investigator or his representative to be incompatible with the study,
• • Subject whose cooperation and understanding do not allow strict compliance with the conditions laid down in the protocol,
• • Pregnant or breast-feeding women,
• • Beneficiary of a legal protection measure.
• Inclusion Criteria Healthy Volunteers:
• • Subject over 18 years of age,
• • Subject free of any treatment in the 7 days preceding inclusion, in particular no use of analgesics, or judged by the investigator or his representative to be compatible with the study
• • Subject with no history of cancer,
• • Subject considered to be in good health by the investigator,
• • Sufficient cooperation and understanding to comply with the study requirements,
• • Agreement to give oral consent to the study,
• • Affiliation with the French Social Security system,
• Exclusion Criteria Healthy Volunteers:
• • Subjects with a medical and/or surgical history judged by the investigator or his representative to be incompatible with the trial,
• • Subjects whose cooperation and understanding do not allow strict compliance with the conditions laid down in the protocol,
• • Pregnant or breast-feeding woman,
• • Participating in another clinical trial, or within the exclusion period, or having received a total amount of compensation exceeding 4500 euros over the 12 months preceding the start of the trial,
• • Benefiting from a legal protection measure.