Ketorolac Effects on Post-operative Pain and Lumbar Fusion

Launched by UNIVERSITY OF MARYLAND ST. JOSEPH MEDICAL CENTER · Jul 15, 2024

Keywords

ClinConnect Summary

This clinical trial is studying the effects of a medication called Ketorolac on pain management for patients undergoing surgery to fuse one or two levels of their spine. The main goal is to see if Ketorolac can help reduce the amount of opioid pain medication needed by patients in the first two days after their surgery. Additionally, the study will check if using Ketorolac affects the success of the spinal fusion and whether it can help patients leave the hospital sooner after their surgery.

To be eligible for this study, participants must be between 18 and 85 years old and scheduled for an elective spinal fusion surgery. They should be in good health overall and not have certain conditions, such as kidney problems or a history of cancer treatment in the last six months. If you join the study, you will receive either Ketorolac or a placebo (a treatment without active medication) without knowing which one you got. This helps ensure that the results are fair and accurate. It's important to note that the study is not yet recruiting participants, but it aims to provide valuable information about pain management after spinal surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 18-85 years of age
• • Elective posterior lumbar instrumented fusion
• • One- or two-level fusion
• • Consent to participate in study, and willing to adhere to study follow up
• Exclusion Criteria:
• • - - Under age of 18 y/o or over age 85.
• • History of renal failure, dialysis or creatinine over 1.50mg/dl
• • Active smoker or history of within the last 6 months
• • Revision surgery
• • Auto/worker compensation
• • Active cancer or history of chemotherapy in last 6 months
• • Active narcotic use within 3 months of surgery date.
• • Infection at operative levels
• • Any allergies to NSAIDs or Opioids