Cellular Immunity, Neuroendocrine, and Inflammatory Factors for Clinical Prognosis in Acute Coronary Syndrome

Launched by HOSPITAL DE CLINICAS JOSÉ DE SAN MARTÍN · Jul 16, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how the body’s stress and inflammatory responses affect patients with Acute Coronary Syndrome (ACS), which is a serious heart condition. Researchers are specifically looking at levels of cortisol (a stress hormone) and C-reactive protein (a marker of inflammation) to see if they can help predict how well patients will do during and after their hospital stay. By tracking these changes in patients admitted to the Coronary Care Unit, the study aims to better understand the impact of these factors on recovery and health outcomes.

To participate in this trial, patients need to be over 21 years old and diagnosed with ACS. They must also agree to join the study. However, those with certain conditions, like severe liver problems or recent heart attacks, will not be eligible. Participants will be monitored during their hospital stay and will receive follow-up calls for up to six months after discharge to check on their health. This study is currently looking for new participants, and it could help improve care for future patients with heart issues.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Are over 21 years of age and admitted to the Coronary Unit of the Hospital de Clínicas with a diagnosis of Acute Coronary Syndrome (ACS).
• • Agree to participate in the study through informed consent.
• Exclusion Criteria:
• • Concomitant diagnosis of chronic neoplastic or inflammatory disease.
• • Diagnosis of allergic disease, parasitic disease, asthma, or hypereosinophilic syndrome.
• • Severe associated valvular disease.
• • Acute myocardial infarction (AMI) in the previous month.
• • Chronic corticosteroid treatment.
• • Creatinine clearance \<30% by MDRD (Modification of Diet in Renal Disease).
• • Severe hepatic insufficiency.
• • Pregnant women.
• • Known disease that limits their life expectancy to 6 months.
• • Refuse to participate in the study either by their own will or unable to understand its characteristics due to their clinical condition.