Role of Topical Steroid Injection With Refractory Benign Esophageal Stricture Endoscopic Dilatation in Children

Launched by MOHAMMAD DABOOS · Jul 22, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a new treatment for children with a condition called refractory benign esophageal stricture, which means their esophagus is narrowed and makes it difficult to swallow. The researchers want to see if combining a special steroid injection with a procedure to widen the esophagus (called endoscopic dilatation) can improve their swallowing ability over a year. The trial includes 21 children under 14 years old who have not previously received steroid injections during their treatment for this condition.

If your child is eligible and participates, they will undergo an endoscopy, where a thin tube with a camera is used to see the stricture, followed by a procedure to stretch it and then inject the steroid directly into the narrowed area. The team will monitor your child's progress over 12 months by checking how often they need further treatments and how well they can swallow. This trial is currently looking for participants, so it's a great opportunity to explore a potential new therapy for managing this challenging condition.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Pediatric patients aged less than 14 years
• • with refractory benign esophageal strictures
• • received a dilatation therapy without triamcinolone injections
• Exclusion Criteria:
• • failure to pass a guide wire secondary to pharyngeal stenosis
• • tracheo-esophageal fistula
• • those who received triamcinolone injections at early dilatation