Evaluation of the Effects of Probiotic Toothpastes on Periodontal Health
Launched by KUTAHYA HEALTH SCIENCES UNIVERSITY · Jul 21, 2024
Trial Information
Current as of June 26, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
Periodontitis is characterized by the progressive destruction of all periodontium structures that support the teeth, including periodontal connective tissue and alveolar bone, caused by dental biofilm, resulting in irreversible damage. Severe periodontitis has become a public health problem that affects approximately 11% of the world's population, that is, 743 million people. When left untreated, it reduces the quality of life and leads to tooth loss. In addition to being a common cause of tooth loss, severe periodontitis has been reported to be a predisposing factor in the development of m...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. Being over 18 years old
- • 2. Pocket depth ≥ 4 mm and clinical attachment loss ≥ 1 mm in at least 5 teeth, bleeding score on probing 20%, and widespread bone loss that can be diagnosed radiographically.
- • 3. Absence of any systemic disease
- • 4. Having at least 14 natural teeth
- • 5. Diagnosing periodontitis as a result of clinical and radiological examinations
- • 6. Volunteering to participate in the research and signing the consent form prepared in accordance with the Declaration of Helsinki.
- Exclusion Criteria:
- • 1. Being outside the specified age range
- • 2. Being pregnant or lactating
- • 3. Having used antibiotics for any reason in the last 3 months
- • 4. Having had periodontal treatment in the last 6 months
About Kutahya Health Sciences University
Kutahya Health Sciences University is a premier academic institution dedicated to advancing healthcare through innovative research and clinical trials. Committed to fostering excellence in medical education and patient care, the university collaborates with leading researchers and healthcare professionals to conduct cutting-edge studies aimed at improving health outcomes. With a focus on translating scientific discoveries into practical applications, Kutahya Health Sciences University plays a vital role in shaping the future of healthcare through rigorous clinical research and interdisciplinary collaboration.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Kütahya, , Turkey
Patients applied
Trial Officials
Berceste Guler Ayyildiz
Principal Investigator
Kutahya Health Science University
Ahu Uraz Corekci
Principal Investigator
Izmir Democracy University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported