The Effects of Different Ventilation Modes on Patients With Pulmonary Lobe Resection

Launched by MAO ENTING · Jul 17, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how different ways of providing breathing support, called ventilation modes, affect patients who have had part of their lung removed due to conditions like lung injury or inflammation. The goal is to see how these ventilation methods impact the body's inflammatory responses and overall breathing function after surgery.

To be eligible for this study, participants should be between 18 and 75 years old and meet certain health criteria, including being prepared for lung surgery and not having serious ongoing respiratory conditions or recent infections. If you join the trial, you can expect to receive different types of breathing support during your recovery, and your health will be closely monitored. This study is currently looking for participants, and it aims to help improve care for patients undergoing lung surgery in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Comprehensive examination and analysis of imaging, laboratory examination and other comprehensive examinations, the diagnosis is clear, which is in line with lobe resection surgical indications
• • Age 18-75 years old, the gender is not limited;
• • ASA grading Ⅰ \~ III level;
• • It is expected that the single lung ventilation time is ≥1 hours, and ≤3 hours
• Exclusion Criteria:
• • Emergency surgery;
• • There is a taboos on the existence of systemic anesthesia;
• • There is a history of acute chronic upper respiratory infections in the past January;
• • Previous bronchial asthma, chronic obstructive pulmonary disease, bronchial dilatation, phthisis ,aspergillosis , acute respiratory distress syndrome or history of respiratory failure;
• • Merge the function of important organs such as heart, liver, and kidney;
• • There was a history of chest surgery and the history of trauma;
• • Preoperative lung function test obvious abnormal abnormal abnormalities (1 second of exhalation (FEV1) \<60%);
• • Patients refuse to participate in the clinical trial