Effect of Allulose on Diet-induced Thermogenesis

Launched by TORONTO METROPOLITAN UNIVERSITY · Jul 17, 2024

Keywords

ClinConnect Summary

This clinical trial is exploring how a sweetener called allulose affects how our bodies burn calories from food, manage blood sugar levels, and how hungry we feel after eating. Researchers are particularly interested in how different amounts of allulose might influence these factors in healthy adults.

To participate in this study, you need to be between 18 and 45 years old, a non-smoker, and have a healthy body weight (a body mass index or BMI between 20 and 24.9). If you have certain health conditions, like diabetes or gastrointestinal issues, or if you've recently had major health events, you may not be eligible. If you join the study, you can expect to take part in tests that measure how your body responds to allulose, while being monitored in a safe environment. This trial is currently looking for participants, so if you're interested, it could be a great opportunity to contribute to understanding how this sweetener works in our bodies!

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Participants (18 - 45 years) who are considered healthy, are non-smokers, and have a body mass index (BMI) between 20 and 24.9 kg/m2 \[World Health Organization classification of normal weight BMI\].
• Exclusion Criteria:
• • Participants who have a fasting plasma glucose \> 5.5 mmol/L indicative of impaired fasting glucose, previously diagnosed diabetes, known or uncertain pregnancy status at the screening visit, gastrointestinal disease, liver or kidney disease, have undergone a major medical or surgical event within the past 6 months, were or are on a diet, skip breakfast, smoke or have taken medication which would be a potential confounder with effects on metabolic and intake regulation.
• • Those unable to complete the testing protocols or are intolerant or allergic to test-day ingredients.